epidemiology of sporadic cases of human enterovirus 92 in captivated primates with acute diarrhea

results sequence analysis indicated that echovirus shared the highest nucleotide identity (85%) with the ev92 strain isolated from the rhesus macaques with gastroenteritis from a us primate center. phylogenetic analysis showed that the ev92 isolated in this study had clustered together with other echoviruses isolated from the primates. conclusions the results suggested that ev92 as a new echovirus may cause acute diarrhea in m. mulatta. background enteroviruses are among the most common viruses, which cause more than one billion infections worldwide. enterovirus 92 (ev92) is a newly identified virus, about which few epidemiological data are available. objectives the aim of this study was to investigate the echoviruses in captive rhesus macaques (macaca mulatta) with acute diarrheal disease in the southwest of china. materials and methods stool samples (246) of diarrheal monkeys were collected for detection of ev92 by reverse transcription pcr (rt-pcr) as well as analysis of the epidemiological characterizations.